An endoscopic full-thickness plication (eFTP) using the GERDX-System may be an alternative for patients with persistent gastroesophageal reflux disease (GERD) that is not adequately controlled with medication or in cases where long-term treatment is not an option.

The GERDX-System, which is less invasive, has less side effects, and doesn’t restrict future therapy options, fills the significant treatment gap between prescription medications and more invasive surgical procedures.

Gerdx Non-Surgıcal Solutıon To The Reflux Problem

The endoscopic procedure known as GERDX has been used to treat reflux illness all over the world for more than ten years.
Gastric acid pathologically flows from the stomach into the oesophagus in a condition known as reflux.

The cause of this is that when the valve preventing gastric fluid from leaking into the oesophagus is ordinarily loose, it prevents this from happening.

Drug treatment, surgical treatments, and endoscopic methods are the three categories into which treatment approaches can be separated.
Drug treatment programmes typically offer patients momentary respite, but they do not produce outcomes by offering permanent solutions.

The success rate of surgical treatment is higher than that of pharmacological treatment, although both have drawbacks for the patient.
Compared to medication therapy, surgical treatment has a better success rate.

The general anaesthetic impact that the patient experiences during the procedure and the surgical wounds that result in the patient make this treatment less popular with patients, which is a drawback of the surgical approach.

While laser treatments have a success rate of 40–45%, another endoscopic therapy approach called GERDX has a success rate of 90%.
Anesthesia is required for the endoscopic GERDX procedure, which takes about 45 minutes on average.

In GERDX, the looseness in the lid—which prevents gastric juice from escaping—is tightened using what we may refer to as stapling by endoscopic means. Since there is no surgery involved, the patient can resume normal activities after six hours of observation. Due to the comfort of the patient and its high success rate, it is the most popular method in Europe and America.


Procedure of Treatment

Patients with gastroesophageal reflux disease (GERD) and a hiatal hernia up to 3 cm may benefit from the minimally invasive GERDX-Procedure.
The technique is carried out from within the patient’s stomach while being directly observed via an endoscope, much like a gastroscopy.
The GERDX-System is less invasive, has far fewer adverse events, and achieves clinical results comparable to those of the most widely used surgical procedures—all without limiting possibilities for subsequent treatments.

Step 1
Under general anaesthesia or severe sedation, the patient’s stomach is used to accomplish the incisionless surgery. The Applicator can be delicately inserted into the stomach through the mouth and oesophagus with the use of a flexible endoscope and a guidewire. The arms of the Applicator are open, and the front portion is fully retroflexed for endoscopic visualization.

Step 2
The stomach wall is retracted into the open arms of the Applicator by the Tissue Retractor after it has been advanced deeply into the gastric cardia mucosa. A large amount of tissue can be gathered for the subsequent suturing procedure thanks to the layout of the manipulating arms and the Tissue Retractor, which is positioned in the centre.
Due to the integrated endoscope’s independence from the applicator, the entire procedure may be perfectly visualized.

Step 3
Under visualization, the Applicator’s arms are closed, establishing an endoscopic full-thickness plication (eFTP) over the entire thickness of the stomach wall. It is crucial to sew through every layer of the stomach wall since this sets up a long-lasting result.

Step 4
The Tissue Retractor has been taken out, the Suture System has been applied, and the Applicator’s arms have been opened once more. The gastro-esophageal connection is fully duplicated and tightly closed around the shaft of the applicator thanks to the pre-tied transmural pledget suture. Additionally, by encircling the tissue, the natural flap-valve is once more produced. The Applicator is then straightened and removed from the patient after the arms have been closed once more.

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